TABLE 2. COMPILATION OF PROSPECTIVE STUDIES ON POST-EXERCISE SYNCOPE.
Prospective studies in which pre-syncopal rates during head-up tilt or tolerance to lower body negative pressure were assessed during recovery from exercise.
| Reference | Exercise | Environment | Incidence |
|---|---|---|---|
| 1 Moderate-intensity exercise | |||
| Mayerson, 1944 | 10 min cycling @ 45 w | 24 to 32°C | 54% pre-syncopal; 60 to 75 head-up tilt [15 min] |
| Gratze et al., 2008 | 42.2 km marathon | 20°C, 78% humidity | 27% pre-syncopal; active standing [6 min] |
| Privett et al., 2010a | 42.2 km marathon | 10 to 11°C, light rain | 10% pre-syncopal; active standing [3 min] |
| Murrell et al., 2009 | 4.5 h running @ 70–80% maximal heart rate | 15°C, 72% humidity | 81% pre-syncopal; 60 head-up tilt [15 min] |
| Eichna et al., 1947a | 51.5 km hike with pack | “Moderately warm” | 54% pre-syncopal; 70 head-up tilt [5 min] |
| Holtzhausen & Noakes, 1995 | 80 km ultra-marathon | 14 to 25°C, 44 to 24% humidity | 23% pre-syncopal; active standing [10 min] |
| 2 High-intensity exercise | |||
| Brogdon & Hellebrandt, 1940 | Brief “violent” exercise | n/a | 2 out of 3 pre-syncopal; active standing |
| Eichna et al., 1947a | Maximal exercise for up to 5 min | 23°C | 58% pre-syncopal; 70 head-up tilt [5 min] |
| Bjurstedt et al., 1983 | Graded maximal cycle test | 21°C | 83% pre-syncopal; 70 head-up tilt [6 min] |
| Privett et al., 2010b | Graded maximal treadmill test | 23°C | 100% pre-syncopal; active standing [10 min] |
| Lacewell et al., 2013 | Supra-maximal exercise for 1 min [modified Wingate test] | 23°C, 40% humidity | 58% pre-syncopal; 60 head-up tilt [15 min] |
| 3 Exercise in the heat | |||
| Luft et al., 1976 | 2 h intermittent cycling @ 30% VO2max | 50°C, 15% humidity | Lower body negative pressure tolerance was reduced 31% |
| Shvartz et al., 1977 | 3 h bench stepping @ 40 w | 39°C, 50% humidity | 46% pre-syncopal; leaning upright against wall [20 min] |
| McCord et al., 2008 | 45 min running @ 50% VO2max | 35°C, 30% humidity | 53% pre-syncopal; 60 head-up tilt [15 min] |
| 4 Exercise at altitude - No prospective studies | |||
| 5 Resistance exercise - No prospective studies | |||