A- HemSC suspended in Matrigel with α6-integrin blocking mAb or control mAb and injected s.c. into nude mice. Representative photographs of Matrigel explants at day10 after injection with corresponding histological sections stained with H&E. Black arrowheads point to luminal structures with red blood cells. Scale bar = 50 μm.
B- Quantification of lumens with red blood cells, reported as vessels/mm2. Data are mean ± SEM.
C- Immunohistochemical staining for human CD31 in implants after 10 days (scale bars, 50 μm).