Table 2.
Non-serous cases with HR mutations.
| Histology | ID | Grade | Germline HR mutationa | Somatic HR mutation(s)a | Somatic PTEN mutation(s)a |
|---|---|---|---|---|---|
| Clear cell | UW400 | 3 | CHEK2 p.S428F | ||
| UWf14 | 3 | BRCA2 p.S368X | |||
| UW420 | 3 | CHEK2 del exon 1–7 | |||
| UW408 | 3 | ATM c.5441delT | PTEN c.678delC | ||
| UW358 | 3 |
BRCA1 1135insA BRIP1 c.3260insA MRE11A c.1196insTT |
PTEN c.968insA | ||
| Endometrioid | UW383 | 1 | BRIP1 p.R798X | PTEN c.955delACTT | |
| UW381 | 1 | ATM c.3284(+1)G>C splice | |||
| UW131 | 2 | BRCA2 p.R2494X | |||
| UW341 | 2 | BRCA1 dup exon 21–24 | |||
| UW165 | 3 | BRCA1 187delAG | |||
| UWf2 | 3 | BRCA2 3034delAAAC | |||
| UW132 | 3 | RAD51D c.580delA | PTEN c.389delG | ||
| Carcinosarcoma | UWf77 | 3 | BRCA1 2080delA | ||
| UW435 | 3 | FAM175A c.1106insG | |||
| UW407 | 3 | RAD51C c.706(−2) A>G splice | |||
| UW124 | 3 | BRCA1 3481delA | |||
| Malignant Brenner’s | UW96 | 3 | FAM175A c.1106insG |
a
BRCA1 and BRCA2 mutations were annotated using BIC designation (http://research.nhgri.nih.gov/bic/, reference sequences: BRCA1 GenBank U14680; BRCA2 GenBank U43746); all other mutations were annotated using HGVS nomenclature.