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. Author manuscript; available in PMC: 2015 Feb 15.
Published in final edited form as: Cancer Res. 2014 Feb 10;74(4):979–1004. doi: 10.1158/0008-5472.CAN-13-2387

Figure 1.

Figure 1

Principles of photoacoustic imaging (PAI) presented for a potential clinical application: diagnostic breast imaging by integrated real-time photoacoustic/ultrasound imaging. The laser sends nano-second pulses of near-infrared light through the transducer into the tissue. This light is then absorbed inside the tissue (at different levels for each tissue type/component) causing a localized transient thermoelastic expansion. This expansion leads to the emission of pressure waves (ultrasound), which can be detected by the array in the transducer. Finally, a photoacoustic image is calculated and displayed in real-time. At the same time, the ultrasound system can be used in its b-mode to provide structural information about the tissue, in addition to the functional/molecular information obtained by PAI, and both images can be displayed on the view