Table 1. Characteristics of γ-H2AX-enriched sequences.

DNA feature analyzed for overlap	WT (%)	KO (%)
Encode clustered TFBS	35.1	55.8*
DNAse clusters	45.5	62.8*
CpG islands	4.5	11.4*
Lamin-associated domains	33.9	1.4*
Caco-2 CTCF peaks	6.3	11.0*
HCT116 methyl sequencing peaks	5.1	23.1*
K562 and MCF7 identified origins of replication	12.7	36.7*

*P<0.001