Table 2a. p16INK4A staining of 69 patients with HNSCC.
| All | p16INK4A+/− | % Positive | P-value |
|---|---|---|---|
| N=69 | 13 | 18.8 | |
| Localization | |||
| Oral cavity | 1/7 | 12.5 | 0.626 |
| Tonsilla | 1/3 | 25 | 0.745 |
| Oropharynx | 7/14 | 33.3 | 0.042* |
| Hypopharynx | 0/13 | 0 | 0.054 |
| Larynx | 2/9 | 18.2 | 0.951 |
| Nasopharynx | 2/4 | 33.3 | 0.342 |
| Other | 0/6 | 0 | 0.217 |
| Histology | |||
| Keratinizing SCC | 6/38 | 13.6 | |
| Non-keratinizing SCC | 5/17 | 22.7 | 0.064 |
| Other | 2/1 | 66.7 | |
| T-status | |||
| T1 | 4/7 | 36.4 | |
| T2 | 2/12 | 14.3 | |
| T3 | 3/14 | 17.6 | 0.527 |
| T4 | 4/20 | 16.7 | |
| Tx | 0/3 | 0 | |
| N-status | |||
| N0 | 4/18 | 18.2 | |
| N1 | 1/10 | 9.1 | |
| N2 | 7/26 | 21.2 | 0.678 |
| N3 | 0/1 | 0 | |
| Nx | 1/1 | 50 | |
| M-status | |||
| M0 | 10/45 | 18.2 | |
| M1 | 2/9 | 18.2 | 0.895 |
| Mx | 0/1 | 0 | |
Abbreviation: SCC, squamous cell carcinoma
*
denotes statistical significance (P<0.05, chi-square)