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A) Norepinephrine reuptake is dose dependently inhibited by both dezocine and nisoxetine. However, inhibition is weaker in the case of dezocine. B) Serotonin reuptake is concentration dependently inhibited in the presence of dezocine and nisoxetine with comparable potency. The relationship is plotted using the following model: Y=Bottom + (Top-Bottom)/(1+10^((LogEC50-X)*HillSlope)).
