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. 2013 Jul 4;5(8):1165–1179. doi: 10.1002/emmm.201302679

Figure 6.

Figure 6

Association of NPGPx genetic polymorphisms with body mass index (BMI) in human
  1. Genomic location of single nucleotide polymorphism (SNP) adjacent to the human NPGPx gene. The allele frequency of each SNP in the HapMap database is shown in pie charts. YRI: Yoruba in Ibadan, Nigeria; JPT: Japanese in Tokyo, Japan; CHB: Han Chinese in Beijing, China; CEU: CEPH Utah residents with ancestry from northern and western Europe.
  2. The association of SNP rs835337 with BMI in 1430 adults of the British 1958 Birth Cohort (B), 4758 adults in the North Finland Birth Cohort (C) and 760 Han Chinese (D).
  3. Association of SNP rs835337 genotypes with NPGPx expression measured by qRT-PCR in abdominal adipose tissue of 84 Han Chinese.
  4. Association of SNP rs835337 genotypes with serum malondialdehyde levels.
  5. Proposed mechanism by which NPGPx modulates adipogenesis. All values are presented as means ± S.E.M.