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. 2013 Jul 4;5(8):1180–1195. doi: 10.1002/emmm.201202034

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© 2013 The Authors. Published by John Wiley and Sons, Ltd on behalf of EMBO

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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Proteomics-based discovery strategy for identification of abnormally expressed nuclear factors in lymphoma

Schematic representation of the overall experimental strategy, as indicated. NAS: nuclear acid-soluble, MS: mass spectrometry.

Heat-map representation of the gene expression levels for 6 candidate ‘off-context’ genes in normal lymphoid and non-lymphoid tissues; PB: peripheral blood [data from BioGPS (Su et al, 2004)].

Heat-map representation of gene expression profiles for 5 ‘off-context’ genes, as indicated; NHL: non-Hodgkin lymphoma, B-CLL: B-cell chronic lymphocytic leukemia, FL: follicular lymphoma, HCL: hairy cell leukemia, MCL: mantle cell lymphoma, BL: Burkitt lymphoma, DLBCL: diffuse large B-cell lymphoma, PEL: primary effusion lymphoma [data from GEO GSE2350 (Basso et al, 2005)].