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. 2014 Feb 13;12(2):926–939. doi: 10.3390/md12020926

Figure 4.

Figure 4

In vitro assay of PPAR-γ activation by phthalimides 7, 11–14 and by rosiglitazone at 1 μM or 10 μM in rat liver Ac2F cells. Con., the negative control, transfected with plasmid containing PPRE and pcDNA3. Rosi, rosiglitazone. Rosiglitazone was used as the positive reference control to monitor the activation of the luciferase reporter. Compound-treated cells were transiently transfected with PPRE plus pFlag-PPAR-γ1. Luciferase expressions (folds of the control) are the means ± SDs (n = 3). * p < 0.05.