Table 3.
Antibacterial activity of butremycin against Staphylococcus aureus ATCC25923, Escherichia coli ATCC 25922 and a selection of methicillin-resistant Staphylococcus aureus (MRSA) strains.
| Strain | Source of Isolate | MIC (µg mL−1) | |
|---|---|---|---|
| Butremycin | Rifampicin | ||
| S. aureus ATCC 25923 a | ATCC | 50 | 0.003 |
| E. coli ATCC 25922 a | ATCC | 50 | 0.01 |
| SMRSA 105 | Toe wound | >50 | 0.007 |
| SMRSA 124 | Open wound | >50 | 0.03 |
| SMRSA 116 | Knee abscess | >50 | 0.01–0.03 |
| EMRSA 15 | Urine infection | 50 | 0.001–0.003 |
a Laboratory strains; All clinical isolates were obtained from the NHS Grampian Microbiology Diagnostic Laboratory, Aberdeen Royal infirmary; Abbreviations: EMSRA = epidemic MRSA, SMRA = Scottish MRSA.