Table 1.
Permuted results.
| Rank | CMAP name | Score | N | Enrichment | P value | Target |
|---|---|---|---|---|---|---|
| 1 | sirolimus | −0.254 | 10 | −0.770 | 0.0000 | mTOR |
| 2 | 17-allylamino-geldanamycin | 0.496 | 18 | 0.611 | 0.0000 | HSP90 |
| 3 | trichostatin A | 0.565 | 12 | 0.714 | 0.0000 | HDACs |
| 4 | LY-294002 | −0.038 | 17 | −0.506 | 0.0001 | PI3 kinase |
| 5 | geldanamycin | 0.544 | 6 | 0.759 | 0.0004 | HSP90 |
| 6 | 5253409 | 0.748 | 2 | 0.971 | 0.0009 | ? |
| 7 | 5224221 | 0.758 | 2 | 0.967 | 0.0015 | ? |
| 8 | vorinostat | 0.684 | 2 | 0.956 | 0.0032 | HDAC |
| 9 | tetraethylene-pentamine | −0.084 | 6 | −0.662 | 0.0055 | proteases |
| 10 | wortmannin | −0.248 | 8 | −0.565 | 0.0071 | PI3 kinase |