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. 2014 Feb 7;4(2):e180. doi: 10.1038/bcj.2014.2

Figure 4.

Figure 4

Cytotoxic effects of anti-CD19-targeted liposomal Rap against SKW6.4 cells and Burkitt's lymphoma cells from patients. (a) In all, 0.5 × 105 SKW6.4 cells were cultured with GL-Rap, CD2-GL-Rap or CD19-GL-Rap containing 1 or 10 nM Rap for 72 h. (b) In total, 0.5 × 105 SKW6.4 cells were cultured with CD19-GL-Rap containing 1 nM Rap for 72 h that had been pretreated with anti-CD19 antibody (0.5 or 1.0 μg/ml) or anti-CD2 antibody (1.0 μg/ml). (c) In all, 0.5 × 105 Burkitt's lymphoma cells from patients were cultured with GL-Rap, CD2-GL-Rap or CD19-GL-Rap containing 1 or 10 nM Rap for 72 h. Cell number was estimated using WST-1 reagent (n=6). *P<0.01.