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. 2014 Jan 9;9(3):484–489. doi: 10.2215/CJN.01990213

Table 3.

Factors at presentation and during follow-up influencing decline in renal function (ml/min per 1.73 m2 per year) by univariate and multivariate linear regression

Characteristic Univariate Multivariate
Regression Coefficients 95% CI P Value Regression Coefficients 95% CI P Value
Age (per 10 yr) 0.05 0.01 to 0.09 0.01 0.01 −0.03 to 0.05 0.63
Sex (women versus men) 0.03 −0.07 to 0.13 0.58
Haas classification
 I/II 1 Reference
 III −0.01 −0.16 to 0.15 0.94
 IV −0.01 −0.21 to 0.18 0.88
 V −0.19 −0.39 to 0.01 0.06
Baseline eGFR (per 10 ml/min per 1.73 m2) −0.02 −0.04 to −0.01 0.01 −0.06 −0.07 to −0.04 <0.001
Baseline proteinuria (per g/d) −0.01 −0.02 to 0.02 0.78
TA proteinuria (per g/d) −0.21 −0.26 to −0.17 <0.001 −0.21 −0.25 to −0.16 <0.001
Baseline MAP (per 10 mmHg) −0.02 −0.06 to 0.02 0.40
TA MAP (per 10 mmHg) −0.19 −0.24 to −0.13 <0.001 −0.15 −0.21 to −0.09 <0.001
Immunosuppressive therapy (yes or no) 0.04 −0.05 to 0.15 0.34
Uric acid (per mg/dl) −0.01 −0.04 to 0.02 0.38

95% CI, 95% confidence interval; TA proteinuria, time-averaged proteinuria; MAP, mean arterial pressure.