Table 3.
Factors at presentation and during follow-up influencing decline in renal function (ml/min per 1.73 m2 per year) by univariate and multivariate linear regression
Characteristic | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
Regression Coefficients | 95% CI | P Value | Regression Coefficients | 95% CI | P Value | |
Age (per 10 yr) | 0.05 | 0.01 to 0.09 | 0.01 | 0.01 | −0.03 to 0.05 | 0.63 |
Sex (women versus men) | 0.03 | −0.07 to 0.13 | 0.58 | |||
Haas classification | ||||||
I/II | 1 | Reference | ||||
III | −0.01 | −0.16 to 0.15 | 0.94 | |||
IV | −0.01 | −0.21 to 0.18 | 0.88 | |||
V | −0.19 | −0.39 to 0.01 | 0.06 | |||
Baseline eGFR (per 10 ml/min per 1.73 m2) | −0.02 | −0.04 to −0.01 | 0.01 | −0.06 | −0.07 to −0.04 | <0.001 |
Baseline proteinuria (per g/d) | −0.01 | −0.02 to 0.02 | 0.78 | |||
TA proteinuria (per g/d) | −0.21 | −0.26 to −0.17 | <0.001 | −0.21 | −0.25 to −0.16 | <0.001 |
Baseline MAP (per 10 mmHg) | −0.02 | −0.06 to 0.02 | 0.40 | |||
TA MAP (per 10 mmHg) | −0.19 | −0.24 to −0.13 | <0.001 | −0.15 | −0.21 to −0.09 | <0.001 |
Immunosuppressive therapy (yes or no) | 0.04 | −0.05 to 0.15 | 0.34 | |||
Uric acid (per mg/dl) | −0.01 | −0.04 to 0.02 | 0.38 |
95% CI, 95% confidence interval; TA proteinuria, time-averaged proteinuria; MAP, mean arterial pressure.