Table 1.
Characteristics of families with MUC1 mutation
| Family Numbera | Ethnicity | MUC1 Mutation (n) | Historically Affected (n) | No MUC1 Mutation (n) | Median Age of ESRD (yr) | Kidney Biopsy (n) | Kidney Ultrasound Available for Review (n) | Prior Linkage to Chromosome 1 |
|---|---|---|---|---|---|---|---|---|
| L1 | Middle Eastern | 11 | 11 | 16 | 42 | 1 | 0 | Yes |
| L2 | African American | 11 | 12 | 20 | 57 | 0 | 6 | Yes |
| L3 | Native American | 22 | 5 | 36 | 45.5 | 8 | 7 | Yes |
| L4 | European American | 7 | 9 | 6 | 60 | 3 | 2 | Yes |
| L5 | European American | 9 | 6 | 0 | 34 | 2 | 0 | Yes |
| L6 | European American | 4 | 5 | 6 | 41 | 0 | 2 | Yes |
| 1 | European American | 3 | 0 | 1 | 28.5 | 1 | 2 | Yes |
| 2 | European American | 3 | 2 | 0 | 67.5 | 2 | 3 | Yes |
| 3 | European American | 1 | 4 | 1 | 42 | 2 | 1 | No |
| 4 | European American | 1 | 5 | 0 | 31.5 | 2 | 1 | No |
| 5 | African American | 2 | 6 | 1 | 29 | 0 | 2 | No |
| 6 | Finnish | 1 | 19 | 0 | 52.5 | 1 | 1 | No |
| 7 | European American | 1 | 9 | 1 | 33.5 | 0 | 1 | No |
| 8 | European American | 1 | 1 | 0 | 31.5 | 0 | 0 | No |
| 9 | European American | 1 | 1 | 0 | 39 | 1 | 1 | No |
| 10 | European American | 2 | 0 | 0 | No members yet with ESRD | 1 | 0 | No |
| 11 | Australian | 2 | 1 | 0 | 31 | 2 | 0 | No |
| 12 | Eastern European | 1 | 0 | 0 | 29 | 1 | 0 | No |
| 13 | Eastern European | 1 | 0 | 0 | 44 | 1 | 0 | No |
| 14 | European American | 6 | 6 | 3 | 43.5 | 2 | 1 | No |
| 15 | Australian | 1 | 2 | 0 | 25 | 2 | 2 | No |
| 16 | Russian | 2 | 1 | 0 | 55 | 1 | 1 | No |
| 17 | Australian | 1 | 1 | 0 | 38 | 0 | 0 | No |
| 18 | Israeli | 1 | 5 | 0 | 39 | 1 | 2 | No |
a
Family number: families L1–L6 refer to the first six families that were linked to chromosome 1 and had mutational analysis performed. Family numbering corresponds to numbering in ref. 8.