Table 1.
Experiment | Tissue type | Age (d.i.v.) | SERUM | Delay | BoNT-A (ng/mL) |
Protection Yes/No |
Experiment duration (h) | |
---|---|---|---|---|---|---|---|---|
# | Conc. | |||||||
BT-016 | SC | 86 | 76 | 0.3% | 0.3 h | 100 | No | 18 |
BT-017 | FC | 28 | 32 | 1.0% | 1.1 h | 100 | No | 8 |
BT-019 | FC | 52 | 83 | 5% | 0.4 h | 100 | Yes | 19 |
BT-068 | FC | 33 | 4 | 5% | 20 h | 50 | Yes | 50 |
BT-070 | FC | 40 | 4 | 1.3% | 3.0 h | 50 | Yes | 15 |
BT-072 | SC | 29 | 4 | 0.5% | 1.2 h | 50 | No | 21 |
BT-074 | SC | 36 | 4 | 1% | 4.2 h | 50 | No | 18.3 |
BT-075 | SC | 37 | 23 | 1% | 2.3 h | 50 | No | 16.8 |
BT-076 | FC | 39 | 23 | 2% | 0.7 h | 50 | Yes | 20 |
BT-077a | FC | 40 | 23 | 2% | 0.3 h | 50 | Yes | 15.2 |
BT-077b | Continuation | 100 | Yes | |||||
BT-077c | Continuation | 150 | Yes | |||||
BT-077d | Continuation | 200 | Yes | 45 |
FC: frontal cortex; SC: spinal cord.
Delay: time between serum addition and BoNT-A addition.