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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Acta Neuropathol. 2014 Jan 3;127(3):397–406. doi: 10.1007/s00401-013-1240-4

Table 4.

TDP-43 burden of patients with TDP-43 Type A pathology

Group C9ORF72 expansion Genotype Age at Death Gender TDP-43 Count
Cohort 1 a Yes GG 90 F 7.7
b Yes CC 83 F 10.5
c Yes CC 74 M 11.0
d Yes CC 71 M 20.5
Cohort 2 e No GG 90 F 4.5
f No CC 84 M 6.0
g No CC 86 M 16.7
h No CC 77 M 24.2

Subjects are homozygous carriers of the minor TMEM106B allele (GG), or of the major TMEM106B allele (CC) in rs3173615. TDP-43 counts were performed in six 10× microscopic fields randomly selected over the gyrus, and averaged for a composite pathologic burden score. Identifiers correspond to Fig. 1.

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