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. 2014 Feb 28;7:18. doi: 10.1186/1755-8166-7-18

Table 1.

Follow-up FISH data for embryos diagnosed with non-mosaic aneuploidy by CMA

Specimen designation TE cell # CMA aneuploidy a Log 2 ratio Abnormal nuclei by FISH (%) b Non-mosaic c Mosaic d Embryo confirmed abnormal e
1 NM
 6
 -X
 -0.501
 100
 Yes
 No
 Yes
-13
 -0.461
 100
 Yes
 No
2 NM
 3
 +15
 0.284
 84
 No
 Yes
 Yes
3 NM
 2
 -X
 -0.721
 37
 No
 Yes
 Yes
+Y
 0.440
 47
 No
 Yes
+21
 0.369
 47
 No
 Yes
4 NM
 2
 -13
 -0.409
 21
 No
 Yes
 Yes
-18
 -0.446
 47
 No
 Yes
5 NM
 6
 -22
 -0.430
 100
 Yes
 No
 Yes
6 NM
 5
 -6
 -0.487
 100
 Yes
 No
 Yes
7 NM
 7
 -14
 -0.374
 94
 Yes
 No
 Yes
8 NM
 7
 +15
 0.300
 94
 Yes
 No
 Yes
9 NM
 2
 -Y
 -0.237
 0
 No
 No
 Yes
+21
 0.465
 92
 Yes
 No
10 NM
 5
 +15
 0.317
 97
 Yes
 No
 Yes
11 NM
 2
 -15
 -0.508
 74
 No
 Yes
 Yes
12 NM
 4
 -19
 -0.382
 91
 Yes
 No
 Yes
13 NM
 3
 +5
 0.294
 80
 No
 Yes
 Yes
+14
 0.249
 83
 No
 Yes
-18
 -0.529
 100
 Yes
 No
14 NM
 3
 -14
 -0.555
 73
 No
 Yes
 Yes
15 NM
 1
 -22
 -0.395
 94
 Yes
 No
 Yes
16 NM
 4
 -8
 -0.642
 97
 Yes
 No
 Yes
+11
 0.336
 97
 Yes
 No
17 NM
 3
 -21
 -0.432
 73
 No
 Yes
 Yes
18 NM
 2
 +9
 0.375
 94
 Yes
 No
 Yes
19 NM
 5
 +16
 0.253
 86
 No
 Yes
 Yes
20 NM
 4
 -22
 -0.407
 87
 No
 Yes
 Yes
21 NM
 3
 -4
 -0.440
 12
 No
 Yes
 Yes
-10
 -1.540
 0
 No
 No
22 NM
 1-2
 -X
 -0.485
 87
 No
 Yes
 Yes
+13
 0.398
 71
 No
 Yes
23 NM
 4
 +8
 0.288
 94
 Yes
 No
 Yes
+22
 0.268
 97
 Yes
 No
24 NM
 8
 -19
 -0.417
 80
 No
 Yes
 Yes
25 NM
 3
 +22
 +0.256
 86
 No
 Yes
 Yes
26 NM 3 -10 -0.561 94 Yes No Yes

aAll chromosomes listed as abnormal in the embryos of this table were identified by BlueFuse software to be aneuploid.

bA nucleus is considered abnormal by FISH if there is a loss or gain of the chromosome identified by CMA to be aneuploid.

cA non-mosaic CMA result is considered concordant with FISH if ≥ 90% of follow-up embryo cells have a FISH signal pattern consistent with the CMA data.

dA mosaic CMA result is considered concordant with FISH if ≥ 10% and < 90% of follow-up embryo cells have a FISH signal pattern consistent with the CMA data.

eAn embryo follow-up result is considered abnormal and concordant with an abnormal CMA result if at least one chromosome in an embryo identified by CMA as abnormal is confirmed by FISH.