Table 2.

Noninfectious pneumonitis severity by NCI Common Toxicity Criteria grade and management, (n=36).

n =	Grade 1	Grade 2	Grade 3	All grades†
Clinical suspicion of NIP	5	28	3	36
mTOR inhibitor therapy
Discontinued*	0	7	2	9
Continued	3	4	0	7
Continued, dose reduced	0	2	0	2
Delayed, dose reduced	0	2	0	2
Delayed, dose maintained	0	1	0	1
NIP intervention
Steroid initiated	2	13	3	18
Antibiotic initiated	1	8	2	11
Bronchodilator initiated	0	3	2	5
Oxygen supplementation	0	0	3	3

^†No patients with grade 4 pneumonitis were identified.

^*Fifteen patients discontinued mTOR inhibitor therapy at time of NIP onset due to progressive disease.