Table 1.
Demographic and clinicopathologic characteristics for subjects in each stage of the multi-stage design
|
Affymetrix microarray |
RT-PCR |
||||||||
|---|---|---|---|---|---|---|---|---|---|
|
Stage 1: non-obese subjects |
Stage 2: obese subjects |
Stage 3: non-obese subjects |
|||||||
| Non-smokers 30 (65%) | Smokers 16 (35%) | p-value | Non-smokers 12 (63%) | Smokers 7 (37%) | p-value | Non-smokers 54 (66%) | Smokers 28 (34%) | p-value | |
| Gender |
|
|
0.2170 |
|
|
0.1698 |
|
|
0.0273 |
| Male |
14 (47%) |
11 (69%) |
|
4 (33%) |
5 (71%) |
|
30 (56%) |
23 (82%) |
|
| Female |
16 (53%) |
5 (31%) |
|
8 (67%) |
2 (29%) |
|
24 (44%) |
5 (18%) |
|
| Age at surgery |
|
|
0.2537 |
|
|
0.8584 |
|
|
0.4597 |
| <50 |
3 (10%) |
3 (19%) |
|
2 (17%) |
1 (14%) |
|
9 (17%) |
5 (18%) |
|
| 50-79 |
24 (80%) |
13 (81%) |
|
9 (75%) |
6 (86%) |
|
41 (76%) |
23 (82%) |
|
| ≥80 |
2 (7%) |
0 |
|
1 (8%) |
0 |
|
4 (7%) |
0 |
|
| Unknown |
1 (3%) |
0 |
|
0 |
0 |
|
0 |
0 |
|
| Nuclear grade |
|
|
0.2032 |
|
|
0.5834 |
|
|
0.2000 |
| 1 |
3 (10%) |
1 (6%) |
|
4 (33%) |
2 (29%) |
|
5 (9%) |
3 (11%) |
|
| 2 |
18 (60%) |
7 (44%) |
|
8 (67%) |
4 (57%) |
|
17 (32%) |
7 (25%) |
|
| 3 |
9 (30%) |
8 (50%) |
|
0 |
1 (14%) |
|
24 (44%) |
11 (39%) |
|
| 4 |
0 |
0 |
|
0 |
0 |
|
8 (15%) |
7 (25%) |
|
| Pathologic tumor stage |
|
|
0.0123 |
|
|
0.5926 |
|
|
0.4713 |
| pT1 |
24 (80%) |
7 (44%) |
|
9 (75%) |
6 (86%) |
|
31 (57%) |
11 (39%) |
|
| pT2 |
2 (7%) |
2 (12%) |
|
2 (17%) |
1 (14%) |
|
4 (7%) |
4 (14%) |
|
| pT3 |
4 (13%) |
7 (44%) |
|
1 (8%) |
0 |
|
18 (33%) |
13 (46%) |
|
| pT4 |
0 |
0 |
|
0 |
0 |
|
1 (2%) |
0 |
|
| Presence of necrosis |
|
|
0.2829 |
|
|
1.0000 |
|
|
0.4739 |
| Yes |
5 (17%) |
5 (31%) |
|
1 (8%) |
1 (14%) |
|
19 (35%) |
13 (46%) |
|
| No |
25 (83%) |
11 (69%) |
|
11 (92%) |
6 (86%) |
|
34 (63%) |
15 (54%) |
|
| Unknown | 0 | 0 | 0 | 0 | 1 (2%) | 0 | |||