Table 2.
Smokers vs non-smokers | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Affymetrix probeset | Gene | Chrom |
Stage 1: non-obese patients |
Stage 2: obese patients |
Combined (stage 1 + stage 2) |
||||||
Fold change in tumor tissue (p-value) | Fold change in normal tissue (p-value) | Interaction p-value | Fold change in tumor tissue (p-value) | Fold change in normal tissue (p-value) | Interaction p-value | Fold change in tumor tissue (p-value) | Fold change in normal tissue (p-value) | Interaction p-value | |||
240292_x_at |
ANKS1B |
12 |
0.92 (0.013) |
1.08 (0.02) |
0.00082 |
0.98 (0.64) |
1.11 (0.005) |
0.018 |
0.94 (0.014) |
1.09 (0.0013) |
0.00005 |
241949_at |
ACOT6 |
14 |
0.88 (0.0098) |
1.07 (0.15) |
0.00085 |
0.89 (0.1) |
1.04 (0.56) |
0.034 |
0.88 (0.0019) |
1.06 (0.13) |
0.00006 |
236999_at |
PPWD1 |
5 |
1.13 (0.0062) |
0.99 (0.74) |
0.0015 |
1.2 (0.0034) |
1.04 (0.5) |
0.038 |
1.14 (0.00023) |
1.0 (0.99) |
0.00016 |
233996_x_at |
EYS |
6 |
0.94 (0.022) |
1.03 (0.27) |
0.0022 |
1.0 (1) |
1.06 (0.045) |
0.046 |
0.96 (0.033) |
1.04 (0.077) |
0.00026 |
241459_at |
LIMCH1 |
4 |
1.27 (0.06) |
0.89 (0.37) |
0.0077 |
1.9 (0.0032) |
1.09 (0.65) |
0.02 |
1.43 (0.0011) |
0.95 (0.62) |
0.00047 |
207568_at |
CHRNA6 |
8 |
0.92 (0.24) |
1.15 (0.064) |
0.0075 |
0.95 (0.62) |
1.23 (0.034) |
0.037 |
0.93 (0.2) |
1.17 (0.0069) |
0.00058 |
210472_at |
MT1G |
16 |
1.0 (0.97) |
1.47 (0.00013) |
0.0045 |
0.93 (0.62) |
1.4 (0.032) |
0.018 |
0.98 (0.82) |
1.45 (0.0000099) |
0.00061 |
242463_x_at |
ZNF600 |
19 |
1.48 (0.0064) |
0.98 (0.87) |
0.0077 |
1.78 (0.001) |
1.31 (0.083) |
0.045 |
1.56 (0.00013) |
1.07 (0.53) |
0.0012 |
210322_x_at |
UTY |
Y |
0.98 (0.76) |
1.13 (0.079) |
0.0086 |
0.96 (0.72) |
1.22 (0.075) |
0.0093 |
0.98 (0.68) |
1.16 (0.012) |
0.00029 |
1557478_at |
NA |
NA |
1.22 (0.03) |
0.95 (0.55) |
0.00052 |
1.88 (0.00002) |
1.31 (0.022) |
0.0011 |
1.38 (0.00012) |
1.04 (0.62) |
0.000002 |
1558410_s_at |
NA |
NA |
1.42 (0.013) |
0.93 (0.58) |
0.0049 |
2.49 (0.0000087) |
1.63 (0.0038) |
0.017 |
1.66 (0.000044) |
1.1 (0.44) |
0.0006 |
210717_at |
NA |
NA |
1.74 (0.00062) |
0.89 (0.47) |
0.0033 |
2.12 (0.00026) |
1.41 (0.053) |
0.027 |
1.83 (0.000011) |
1.03 (0.8) |
0.00086 |
232324_x_at |
NA |
NA |
1.17 (0.004) |
0.97 (0.52) |
0.0081 |
1.27 (0.0018) |
1.03 (0.61) |
0.039 |
1.2 (0.000058) |
0.99 (0.77) |
0.0011 |
232369_at |
NA |
NA |
1.36 (0.021) |
0.89 (0.4) |
0.0081 |
2.07 (0.00065) |
1.3 (0.15) |
0.031 |
1.53 (0.00016) |
1.0 (0.99) |
0.00078 |
244290_at | NA | NA | 1.32 (0.0038) | 0.99 (0.94) | 0.0015 | 1.66 (0.000041) | 1.26 (0.022) | 0.033 | 1.4 (0.000035) | 1.06 (0.42) | 0.00019 |
The smoking status-by-tissue type interaction p-value is provided as well as the fold change of expression in smokers relative to non-smokers and corresponding p-values.
Chrom denotes chromosome.
NA denotes that there is no gene annotation available for the corresponding Affymetrix probeset.