Table 2.
RA Classification by Individual Criteria among Participants in the NHS/NHSII Cohorts Newly Self-Reporting Doctor-diagnosed RA in 2009–2012
| Characteristic, n (%) | Reviewers’ Opinion (n=98) |
Both Criteria Sets (n=72) |
Only ACR 1987 Criteria (n=26) |
Only ACR/EULAR 2010 Criteria (n=9) |
Neither Criteria (n=21) |
|---|---|---|---|---|---|
| 1987 ACR Criteria | |||||
| Morning stiffness > 1 hour | 72 (73.5) | 60 (83.3) | 17 (65.4) | 3 (33.3) | 3 (14.3) |
| Arthritis ≥ 3 joint areas | 95 (96.9) | 71 (98.6) | 26 (100) | 7 (77.8) | 5 (23.8) |
| Hand arthritis | 94 (95.9) | 71 (98.6) | 26 (100) | 6 (66.7) | 9 (42.9) |
| Symmetric arthritis | 93 (94.9) | 70 (97.2) | 25 (96.2) | 4 (44.4) | 2 (9.5) |
| Nodules | 6 (6.1) | 4 (5.6) | 2 (7.7) | 0 (0) | 0 (0) |
| RF positive | 64 (65.3) | 56 (77.8) | 4 (15.4) | 6 (66.7) | 1 (4.8) |
| Radiographic erosions | 29 (29.6) | 22 (30.6) | 9 (34.6) | 0 (0) | 0 (0) |
| 2010 ACR/EULAR Criteria | |||||
| 1 Large Joint | 2 (2) | 0 (0) | 2 (7.7) | 0 (0) | 3 (14.3) |
| 2–10 Large Joints | 2 (2) | 0 (0) | 0 (0) | 2 (22.2) | 3 (14.3) |
| 1 Small Joint | 14 (14.3) | 8 (11.1) | 6 (23.1) | 4 (44.4) | 7 (33.3) |
| 2–10 Small Joints | 43 (43.9) | 29 (40.3) | 16 (61.5) | 1 (11.1) | 5 (23.8) |
| > 10 Large Joints | 35 (35.7) | 35 (48.6) | 1 (3.8) | 2 (22.2) | 0 (0) |
| Negative RF and Anti-CCP | 26 (26.5) | 13 (18.1) | 18 (69.2) | 1 (11.1) | 15 (71.4) |
| Low positive RF or Anti-CCP | 28 (28.6) | 25 (34.7) | 4 (15.4) | 2 (22.2) | 3 (14.3) |
| High positive RF or Anti-CCP | 38 (38.8) | 32 (44.4) | 0 (0) | 6 (66.7) | 1 (4.8) |
| Abnormal CRP or ESR | 63 (64.3) | 45 (62.5) | 14 (53.8) | 7 (77.8) | 9 (42.9) |
| Normal CRP and ESR | 23 (23.5) | 19 (26.4) | 6 (23.1) | 1 (11.1) | 11 (52.4) |
| > Six weeks of symptoms | 96 (98) | 72 (100) | 24 (92.3) | 9 (100) | 18 (85.7) |
RF = Rheumatoid factor, Anti-CCP = anti-cyclic citrullinated peptide antibody, CRP = C-reactive protein, ESR = erythrocyte sedimentation rate