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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Br J Haematol. 2013 Dec 12;164(5):729–739. doi: 10.1111/bjh.12690

Table III.

Logistic regression model for chronic kidney disease stage in the UIC and Walk-PHaSST cohorts.

UIC
N Variables OR* 95% CI p-value
CKD Stage 1 74 Haemoglobinuria
Age
MAP		 12.8
1.5
1.0		 5.3 – 31.1
1.1 – 2.0
0.6 – 1.4		 < 0.0001
0.029
0.8
CKD Stage 2 16 Haemoglobinuria
Age
MAP		 112.0
4.1
1.4		 19.8 – 634.2
2.1 – 7.8
0.7 – 2.9		 < 0.0001
< 0.0001
0.3
CKD Stage 3 or higher 9 Haemoglobinuria
Age
MAP		 110.4
11.7
2.1		 13.7 – 891.1
3.6 – 37.9
0.9 – 5.0		 < 0.0001
< 0.0001
0.092
Walk-PHaSST
N Variables OR* 95% CI p-value
CKD Stage 1 72 Haemoglobinuria
Age
MAP		 4.5
0.9
0.9		 1.9 – 10.7
0.7 – 1.2
0.6 – 1.4		 0.00062
0.4
0.8
CKD Stage 2 12 Haemoglobinuria
Age
MAP		 2.2
3.6
1.0		 0.4 – 12.4
1.7 – 7.3
0.5 – 2.2		 0.4
0.00048
0.9
CKD Stage 3 or higher 22 Haemoglobinuria
Age
MAP		 11.3
3.3
2.8		 3.2 – 40.4
1.8 – 6.1
1.4 – 5.5		 0.00019
0.00020
0.0032
*

Odds ratios are based on the comparison to subjects without CKD.

UIC = University of Illinois at Chicago; Walk-PHaSST = Walk-Treatment of Pulmonary Hypertension and Sickle Cell Disease with Sildenafil Therapy; CKD = chronic kidney disease; MAP = mean arterial pressure; OR = Odds Ratio; 95% CI = 95% confidence interval. Odds ratio for Age and MAP are based on 10-year and 10-mmHg intervals, respectively.