Table 3.

Examples of bacterial and viral antigens that can cross-react with self-antigens with potentially resultant diseases.

Pathogen antigen	Cross-reactive self-antigen	Autoimmune disease
Herpes simplex virus	Corneal antigen	Stromal keratitis
Campylobacter jejuni	Ganglioside in peripheral nerve	Guillain-Barré syndrome
Coxsackievirus	Glutamic acid decarboxylase	Type 1 diabetes
Theiler's murine encephalomyelitis virus	Proteolipid protein	Multiple sclerosis
Yersinia enterocolitica	Thyrotropin receptor	Thyroid autoimmunity
Borrelia burgdorferi	Leukocyte function associated antigen	Lyme arthritis
Salmonella typhi and Yersinia enterocolitica	HLA-B27	Reactive arthritis
HHV-6, EBV, Rubeolla, influenza virus, and HPV	Myelin basic protein	Multiple sclerosis
Streptococcal M protein	Myosin and other heart valve proteins	Rheumatic fever
Trypanosoma cruzi	Cardiac myosis	Chagas heart disease