Table 2.

Associations of baselines cognitive composite scores with vascular factors (cross-sectional, adjusted for demographics.)

	Attention/Speed		Executive Function		Language		Memory		Visuospatial Function
Vascular Variable (see Table 1)	Estimate	P value	Estimate	P value	Estimate	P value	Estimate	P value	Estimate	P value
Stroke	−0.30	<.001	−0.34	<.001	−0.41	<.001	−0.33	<.001	−0.46	<.001
Coronary heart disease	0.04	0.26	0.02	0.62	0.06	0.09	0.04	0.26	−0.04	0.40
Cardiac arrhythmia	−0.002	0.962	-−0.08	0.07	−0.10	0.03	0.01	0.79	−0.05	0.47
Waist: Hip Ratio (WHR)	−0.88	<.001	−0.57	<0.01	−0.55	0.01	−0.11	0.63	−0.02	0.95
Heart failure	−0.06	0.32	−0.09	0.09	0.02	0.75	0.08	0.14	−0.09	0.26
Cholesterol elevation	0.08	0.031	0.05	0.14	0.05	0.16	0.11	<0.005	0.05	0.32
HDL cholesterol >=50 or ApoA1>=120	0.05	0.29	0.10	0.02	0.04	0.39	−0.03	0.46	0.09	0.16
LDL cholesterol >=130 or ApoB>=100	0.01	0.91	0.02	0.68	−0.003	0.95	−0.06	0.16	−0.07	0.29
ApoB: ApoA1 ratio	0.18	0.13	−0.07	0.48	−0.07	0.49	−0.11	0.30	−0.02	0.92
Diabetes mellitus	−0.14	<.001	−0.13	<0.005	−0.06	0.13	0.01	0.77	−0.06	0.25
Diabetes and/or HbA1c >=6	−0.06	0.09	−0.07	0.04	0.001	0.97	0.02	0.55	0.02	0.75
Hypertension and/or Systolic BP>=140	−0.002	0.98	0.04	0.54	−0.03	0.62	0.06	0.27	−0.09	0.28
Diastolic BP >=80	0.06	0.11	−0.09	<0.01	−0.10	<0.01	−0.02	0.61	−0.03	0.47
Homocysteine>=10	−0.02	0.73	−0.03	0.57	−0.05	0.44	−0.03	0.61	−0.07	0.45
CystatinC>=1	−0.09	0.18	−0.04	0.46	−0.06	0.35	−0.13	0.03	0.01	0.91
C-Reactive Protein>=10	−0.14	0.26	−0.28	<0.01	−0.09	0.45	−0.11	0.31	−0.38	0.02
APOE*4 carrier status	0.03	0.52	<.0001	1.00	0.03	0.41	−0.12	<0.01	−0.09	0.12
Previous drinking	0.07	0.20	−0.05	0.39	0.02	0.73	−0.04	0.47	0.01	0.93
Current drinking	0.14	<0.005	0.12	<0.01	0.19	<.001	0.13	<0.01	0.16	0.02
Previous smoking	−0.01	0.74	0.02	0.60	0.02	0.46	0.01	0.85	−0.06	0.16
Current smoking	−0.06	0.42	−0.01	0.87	0.07	0.32	−0.03	0.72	−0.11	0.24