Table 4b.
Categorical Outcomes (≥75th vs <75th percentile) | Exposure | ApoE4− (N=1359) | ApoE4+ (N=364) | P-value for Interaction | ||
---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |||
FAS - % Total errors | Hypertension | 0.86 (0.64–1.15) | 0.30 | 1.68 (0.93–3.03) | 0.08 | 0.04 |
Animals - % Perseverations | Age | 1.02 (1.00–1.03) | 0.03 | 1.06 (1.03–1.10) | 0.0002 | 0.01 |
Animals - % Total Errors | Age | 1.02 (1.01–1.04) | 0.004 | 1.07 (1.03–1.10) | <0.0001 | 0.01 |
Trails B - Total Errors | Age | 1.05 (1.03–1.06) | <0.0001 | 1.01 (0.98–1.03) | 0.63 | 0.006 |
Abbreviations: OR = odds ratio; CI=confidence interval; ApoE4− = apolipoprotein ε4 negative group; ApoE4+ = apolipoprotein ε4 positive group;
All models are adjusted for age, sex, education group (<high school degree, high school degree, college degree, >college degree), and time between risk factor measurement and neuropsychological testing.