Table 2.

The association between covariates and, respectively, LTL, and fatigue.

Covariates	Association with LTL						Association fatigue
	Raw			Adjusted (sex, age)			Raw			Adjusted (sex, age)
	Coef†	CI (95%)	P	Coef†	CI (95%)	P	Coef†	CI (95%)	P	Coef†	CI (95%)	P
Fatigue (Score 0–6)	0.039	0.006–0.071	0.019	0.038 ††	0.005–0.070	0.023
Age	−0.019	−0.035–−0.003	0.018	−0.20	−0.036–−0.004	0.012	−0.041	−0.073–−0.009	0.012	−0.040	−0.072–−0.008	0.014
Sex
Male	Ref			Ref			Ref			Ref
Female	0.161	0.032–0.290	0.014	0.169	0.041–0.297	0.009	−0.169	−0.426–0.088	0.197	−0.154	−0.408–0.099	0.233
Zygosity
MZ	Ref			Ref			Ref			Ref
DZ	−0.027	−0.150–0.097	0.672	−0.039	−0.159–0.081	0.530	−0.020	−0.263–0.223	0.871	−0.047	−0.286–0.192	0.700
Geleffect	0.007	0.000–0.014	0.040	0.002	−0.008–0.011	0.688
Smoking
Never	Ref			Ref			Ref			Ref
Former	−0.076	−0.172–0.021	0.124	−0.063	−0.160–0.035	0.206	−0.132	−0.408–0.144	0.349	−0.208	−0.490–0.074	0.148
Current	−0.127	−0.234–−0.020	0.020	−0.122	−0.230–−0.014	0.027	−0.156	−0.448–0.135	0.293	−0.252	−0.547–0.043	0.095
Physical activity (Score 0–4)	0.024	−0.006–0.054	0.122	0.020	−0.011–0.049	0.213	0.344	0.266–0.423	<0.001	0.336	0.257–0.415	<0.001
BMI	−0.010	−0.022–0.003	0.137	−0.010	−0.023–0.003	0.127	−0.039	−0.072–−0.006	0.019	−0.052	−0.085–−0.018	0.002
Cognitive function	0.014	−0.000–0.027	0.053	0.011	−0.009–0.025	0.111	0.041	0.005–0.077	0.025	0.038	0.002–0.074	0.037
Depression symptomatology	−0.012	−0.022–−0.002	0.022	−0.012	−0.022–−0.002	0.024	−0.120	−0.145–−0.094	<0.001	−0.118	−0.143–−0.093	<0.001
Cancer
No	Ref			Ref			Ref			Ref
Yes	−0.005	−0.122–0.113	0.940	−0.010	−0.127–0.107	0.868	−0.230	−0.588–0.129	0.209	−0.236	−0.592–0.120	0.194
CVD
No	Ref			Ref			Ref			Ref
Yes	−0.009	0.095–0.076	0.829	−0.013	−0.098–0.072	0.763	−0.173	−0.414–0.068	0.160	−0.167	−0.406–0.072	0.171
Diabetes
No	Ref			Ref			Ref			Ref
Yes	0.001	−0.191–0.192	0.997	0.006	−0.184–0.196	0.952	−0.297	−0.852–0.257	0.293	−0.266	−0.817–0.284	0.343
Rheumatic
No	Ref			Ref			Ref			Ref
Yes	0.004	−0.080–0.087	0.933	−0.011	−0.095–0.072	0.788	−0.414	−0.656–−0.179	0.001	−0.419	−0.659–−0.179	<0.001

Bold values mark the significant adjusted coeffients.

^†The coefficients shows the magnitude of the linear association between covariates and LTL respectively fatigue. First columns are raw data, while second columns are adjusted for sex and age.

^††There is a significant association between LTL and fatigue when adjusting for age and sex. The coefficient of 0.038 tells that for every increase on the fatigue score (i.e. the less fatigued) the LTL is 0.038 kb longer.