Table 1.
Characteristics of patients included in RISG1.
| Aalborg | Copenhagen | All | P | |
|---|---|---|---|---|
| Participants, n (%) | 167 (80.3) | 41 (19.7) | 208 (100) | — |
| Sex, F/M (% F) | 138/29 (82.6) | 38/3 (92.7) | 176/32 (84.6) | 0.15 |
| Age years, median (IQR) | 44 (34–53) | 47 (36–55) | 45 (35–53) | 0.55 |
| Previously hyperthyroid, n (%) | 12 (7.2)** | 0 (0) | 12 (5.8) | — |
| Smoker, n (%) | 45 (26.9) | 11 (26.8) | 56 (26.9) | 1.00 |
| Estrogen use, n (%) | 29 (21.0) | 3 (7.9) | 32 (18.2) | 0.93 |
| GD in 1st generation relatives, n (%) | 42 (25.3)* | 11 (26.8) | 53 (25.5) | 0.87 |
| Body height cm, median (IQR) | 168 (163–173) | 167 (162–172) | 168 (163–172) | 0.25 |
| Body weight kg, median (IQR) | 65.3 (57.8–78.1) | 60.0 (53.5–68.5) | 64.5 (57.5–75.9) | 0.007 |
| BMI kg/m2, median (IQR) | 23.5 (21.1–26.2) | 22.0 (19.9–23.8) | 22.9 (20.8–26.0) | 0.011 |
| Graves' orbitopathy, n (%) | 51 (30.5) | 5 (12.2) | 56 (26.9) | 0.018 |
| S-T4 nmol/L, median (IQR) | 213 (177–269) | 189 (167–238) | 201 (175–255) | 0.086 |
| S-T3 nmol/L, median (IQR) | 5.5 (4.3–7.5) | 5.0 (3.5–6.3) | 5.4 (4.2–7.1) | 0.021 |
| S-TRAb IU/L, median (IQR) | 9.1 (5.1–14) | 9.7 (5.4–22)* | 9.1 (5.2–15.2) | 0.37 |
| S-TPO kU/L, median (IQR) | 277 (33–2295) | 230 (30–3600)*** | 266 (30–2717) | 0.80 |
| Thyroid volume mL, median (IQR) | 21.1 (15.8–34.3)* | 16.0 (10.0–24.0)* | 20.0 (14.5–31.9) | <0.001 |
P for comparison between Aalborg and Copenhagen participants using Mann-Whitney U test or the Pearson χ 2/Fisher's exact test as appropriate. F: female. M: male. IQR: 25–75% interval. GD: Graves' disease.
*One value missing.
**Two values missing.
***Three values missing.