Skip to main content
. 2014 Mar 6;10(3):e1004158. doi: 10.1371/journal.pgen.1004158

Figure 5. Summary of statistical comparison between ANOVA identified genes and genes differentially expressed after IVD.

Figure 5

ANOVA interaction identified 403 genes both differentially methylated and differentially expressed between OSIS- and EIUM-. The gene expression array identified 4,764 differentially expressed transcripts between OSIS+ and EIUM+. The intersection of these two gene lists identified 271 common genes (shown at the top in hashed blue and white). In the same fashion, we examined the gene ontology cellular process terms that were similar between the two groups, to look for differentially methylated genes and transcription factors that may serve as pathway hubs during IVD. The most overrepresented terms were determined for the both groups of genes. The intersection of similar GO terms was then sorted based on p-value (bottom left), and the gene symbols for transcription factors common to both groups that contributed to this list of GO terms are listed (bottom right).