Table 1. Characteristics of human pancreatic islet donors included in the genome-wide analysis of DNA methylation in pancreatic islets.
Non-diabetics (n = 34) | T2D (n = 15) | P-value | |
Gender (Males/Females) | (22/12) | (10/5) | |
HbA1c (%) | 5.4±0.4 | 6.9±1.0 | 1.2×10−11 |
Age (years) | 56.0±9.0 | 59.5±10.7 | 0.2 |
BMI (kg/m2) | 25.9±2.3 | 28.3±4.7 | 0.06 |
Glucose-stimulated insulin secretion (ng/islet·h) at 16.7 mM glucose | 1.24±1.40 | 0.74±1.23 | 0.04 |
Mann-Whitney U test was used for statistical analysis and data are presented as mean ± SD.