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MG132 increases endogenous PC1 expression and decreases PC2 expression in mIMCD-3 cells. A, mIMCD-3 cells were treated with MG132 (1 μm/ml) for 16 h. Control cells were treated with vehicle (DMSO). Treatment with MG-132 led to an up-regulation of endogenous PC1 and down-regulation of PC2. This is a Western blot, and the entire experiment was repeated three times. B, summary of PC2 expression after proteasome treatment in mIMCD3 cells.
