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Binding of ADAMTS-4 and ADAMTS-5 to LRP1 clusters. Purified LRP1 fragments were coated onto microtiter plates, and binding of ADAMTS-4-1 (0–0.2 μm), ADAMTS-4-2 (0–1 μm), ADAMTS-5-2 (0–0.2 μm), ADAMTS-5-3 (0–1 μm), or ADAMTS-5-4 (0–1 μm) was measured as in Fig. 6.
