. 2014 Jan 20;289(10):6498–6512. doi: 10.1074/jbc.M113.494542

TABLE 1.

MicroCT assessment of trabecular bone architecture of the right femur of mice treated with Siglec-15 antibody

The data represent the mean ± S.E. (n = 5). The abbreviations used are: BV/TV, percent bone volume; Tb.No, trabecular number; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation; BS/TV, bone surface density; Conn.Dn, connectivity density.

	Control IgG	Siglec-15 mAb
BV/TV (%)	6.4 ± 0.60	10 ± 1.8^a
Tb.No (1/mm)	1.23 ± 0.103	2.01 ± 0.336^a
Tb.Th (mm)	0.052 ± 0.0015	0.049 ± 0.0008
Tb.Sp (mm)	0.283 ± 0.0140	0.206 ± 0.0236^a
BS/TV (1/mm)	6.97 ± 0.566	11.1 ± 1.50^a
Conn.Dn (1/mm³)	501 ± 71.5	996 ± 186^a

^a p value control IgG versus Siglec-15 mAb <0.05.