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. 2014 Jan 15;289(10):6551–6564. doi: 10.1074/jbc.M113.533232

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 6. — LPA₁ is up-regulated in bones of ovariectomized mice. A, real time PCR analysis of LPA receptor (LPA_1–6) mRNA expression in bone of OVX- and sham-operated mice. Values are the mean ± S.D. of three mice normalized to housekeeping gene L32. ¶, p < 0.05; ¶¶, p < 0.01; ¶¶¶, p < 0.001 versus SHAM-operated animals using two-sided unpaired t test. B, real time PCR analysis of LPA₁, CTR, and CTSK mRNA expression in bone of OVX- and sham-operated mice and ovariectomized mice treated with zoledronic acid (100 μg/kg) (OVX+Zol). Values are the mean ± S.D. of three mice normalized to housekeeping gene L32. All values are the mean ± S.D. of three mice. *, p < 0.05; ***, p < 0.01 versus SHAM-operated animals. ANOVA with Bonferroni post-test.