FIGURE 4.

Monensin prevents chemLTP-induced increases in GABA_BR surface expression. A, hippocampal neurons were transfected with HA-GABA_B2 and subjected to the glycine chemLTP protocol in either the presence or absence of 1 μm monensin (Monen) for the times indicated. Surface expressed GABA_BRs were visualized with HA antibody. B, quantification of surface expression of HA-GABA_B2 containing receptors at 0, 10, and 20 min after LTP induction as described in A. **, p ≤ 0.01 (n = 4–5 cells per condition).