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EmrE binds and transports a broad range of ligands. A, chemical structures of the tetrahedral and planar ligand series. B, the EmrE dimer exchanges between an AB and BA conformation (state A in green; state B in blue) as it converts between the inward- and outward-facing conformations. A 90° rotation permits a view of the open and closed faces of EmrE (Protein Data Bank code 3B5D, PyMOL).
