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. 2014 Feb 16;2014:570894. doi: 10.1155/2014/570894

Figure 2.

Figure 2

The Th1 response was suppressed by anti-IL-17A mAb and IL-1Ra treatments. ((a) and (b)) The secretions of IFN-γ and IL-2 in supernatant of the macrophage-lymphocyte cocultured system were assayed by ELISA. ((c), (d), and (e)) The expressions of IFN-γ, IL-2, and T-bet in lymphocytes were assayed by real-time PCR. The concentration of IL-1Ra is 15 μg/mL and the concentration of anti-IL-17A mAb is 20 μg/mL. Data were presented as mean ± SEM (n = 5). #: P < 0.05, significantly different compared with the PBS group. Δ: P < 0.05, significantly different compared with the silica group.