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. 2014 Feb 16;2014:570894. doi: 10.1155/2014/570894

Figure 5.

Figure 5

Th17 differentiation-related cytokines were regulated by IL-1Ra treatment. ((a), (b), and (c)) The secretions of IL-6, IL-1β, and IL-23 in supernatant of the macrophage-lymphocyte cocultured system were assayed by ELISA. ((d), (e), and (f)) The expressions of IL-6, IL-1β, and IL-23 in lymphocytes were assayed by real-time PCR. The concentration of IL-1Ra is 15 μg/mL and the concentration of anti-IL-17A mAb is 20 μg/mL. Data were presented as mean ± SEM (n = 5). #: P < 0.05, significantly different compared with the PBS group. Δ: P < 0.05, significantly different compared with the silica group.