Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Mar 7;5:80. doi: 10.3389/fimmu.2014.00080

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Olofsson, Forslund, Vanherberghen, Chechet, Mickelin, Ahlin, Everhorn and Önfelt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Natural killer cell motile scanning of the target-cell surface. (A) Time-lapse sequence showing an IL-2-activated NK cell (black arrowhead) scanning the surface of a target cell. The images are overlaid with a trace of the NK cell trajectory (white) showing that the NK cell moves several laps around the target cell before detaching. Scale bars indicate 10 μm. (B) Fluorescence images corresponding to (A) showing the fluorescently labeled NK cell (red, white arrowhead) and target cells (green). Both transmitted-light and fluorescence images have been resampled. (C) Total distance migrated in conjugation plotted vs. area covered in conjugation for resting (squares) and activated (diamonds) NK cells indicating the conjugation periods fulfilling the three criteria (blue squares and red diamonds for resting and activated NK cells, respectively). (D) Average migration speed in conjugation plotted vs. total distance migrated in conjugation for resting (squares) and IL-2-activated (diamonds) indicating motile scanning behavior (colored symbols). (E) Average migration speed in conjugation plotted vs. area covered in conjugation indicating motile scanning behavior (colored symbols).