Table 1.
Characteristics and clinical profile of subjects.
| Variable | Median (min, max) | p b | ||
|---|---|---|---|---|
| All Subjects (n = 206) | Age < 40 (n = 94) | Age ≥ 40 (n = 112) | ||
| Age (year) | 41 (23, 67) | |||
| BMI(kg/m2) | 23.6 (16.1, 37.2) | 23.5 (16.1, 35.8) | 23.6 (16.5, 37.2) | 0.576 |
| Waist circumference (cm) | 83.5 (61.5, 118.2) | 81.3 (61.5, 118.2) | 84 (67.1, 113) | 0.010 |
| Systolic blood pressure (mmHg) | 131 (99, 193) | 128 (101, 184) | 135.5 (99, 193) | 0.004 |
| Diastolic blood pressure (mmHg) | 81 (52, 124) | 77 (53, 124) | 82 (52, 121) | 0.016 |
| Smoker a | 78 (37.9) | 37 (39.4) | 41 (36.6) | 0.004 |
| Alcohol drinking a | <0.001 | |||
| No | 36 (17.5) | 18 (19.1) | 18 (16.1) | |
| <4 times/week | 84 (40.8) | 52 (55.3) | 32 (28.6) | |
| ≥4 times/week | 86 (41.7) | 24 (25.5) | 62 (55.4) | |
| Exercise a | 0.958 | |||
| No | 91 (44.2) | 42 (44.7) | 49 (43.8) | |
| ≤2 times/week | 71 (34.4) | 31 (32.9) | 40 (35.7) | |
| 3–5 times/week | 29 (14.1) | 15 (16.0) | 14 (12.5) | |
| >5 times/week | 25 (7.3) | 6 (6.4) | 9 (8.0) | |
| Serum retinol (mg/L) | 1.3 (0.0, 2.8) | 1.2 (0.5, 2.6) | 1.4 (0.0, 2.8) | 0.001 |
| Serum α-tocopherol (mg/L) | 6.5 (1.7, 15.4) | 6.5 (1.7, 13.7) | 6.9 (1.7, 15.4) | 0.005 |
| Serum γ-tocopherol (mg/L) | 0.5 (0.1, 4.2) | 0.5 (0.1, 1.7) | 0.6 (0.2, 4.2) | 0.003 |
| TC (mg/dL) | 204 (128, 284) | 193 (128, 284) | 209.5 (137, 277) | 0.010 |
| HDL-c (mg/dL) | 57 (35, 133) | 56 (35, 119) | 59 (35, 133) | 0.259 |
| LDL-c (mg/dL) | 128.5 (53, 209) | 123.5 (53, 209) | 130 (64, 195) | 0.299 |
| TG (mg/dl) | 99.5 (30, 600) | 85 (30, 349) | 110.5 (33, 600) | 0.025 |
| Uric acid (mg/dL) | 6.0 (2.8, 9.2) | 6.1 (2.8, 9.0) | 6.0 (3.4, 9.2) | 0.998 |
| Insulin (μU/mL) | 4.4 (0.5, 30.4) | 4.4 (0.5, 15.5) | 4.4 (1.1, 30.4) | 0.727 |
| Fasting glucose (mg/dL) | 92 (68, 169) | 89.5 (68, 140) | 94 (79, 169) | <0.001 |
| HbA1c (%) | 4.9 (3.7, 7.4) | 4.9 (3.7, 7.1) | 4.9 (4.2, 7.4) | 0.012 |
| HOMA-R | 1.0 (0.1, 8.7) | 1.0 (0.1, 3.5) | 1.0 (0.3, 8.7) | 0.735 |
| Hs-CRP (mg/dL) | 0.3 (0.0, 46.5) | 0.3 (0.0, 46.5) | 0.4 (0.1, 7.4) | 0.767 |
| Serum Fe (μg/dL) | 112 (10, 273) | 118 (31, 273) | 111 (10, 214) | 0.413 |
| Ferritin (ng/ml) | 165.2 (2.8, 785.1) | 149.8 (9.3, 712.8) | 171.1 (2.8, 785.1) | 0.076 |
| NOx (μmol/L) | 25.8 (8.6, 112.4) | 25.1 (8.6, 102.6) | 26.4 (8.9, 112.4) | 0.464 |
| H2O2 (μmol/g creatinine) | 3.0 (0.0, 51.4) | 2.9 (0.0, 41.3) | 3.2 (0.0, 51.4) | 0.304 |
| 8-OHdG (ng/mg creatinine) | 8.5 (2.1, 21.7) | 7.8 (2.7, 21.7) | 9.1 (2.1, 19.6) | 0.028 |
| 8-Isoprostane (pg/mg creatinine) | 654.0 (6.6, 4,372.9) | 658.4 (7.5, 3,408.3) | 640.4 (6.6, 4,372.9) | 0.945 |
Notes: BMI, body mass index; TC, total cholesterol; LDL-c, low-density lipoprotein cholesterol; HDL-c, high-density lipoprotein cholesterol; TG, triglycerides; HbA1c, haemoglobin A1c; HOMA-R, homeostasis model assessment ratio; Hs-CRP, high-sensitivity C-reactive; protein; NOx, nitrogen oxide; H2O2, hydrogen peroxide; 8-OHdG, 8-hydroxy-2’-deoxyguanosine; a n (%); b Mann-Whitney U test or χ2 test.