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. 2014 Mar 7;6:30. doi: 10.3389/fnagi.2014.00030

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Copyright © 2014 Garcia, Ornellas, Martin, Patti, Mello, Frussa-Filho, Han and Longo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plus-maze discriminative avoidance task (PM-DAT) evaluation. The PM-DAT performance of the wild type (WT-SAL) and 2xTg-AD animals (AD-SAL; AD-MSC and AD-MSC-VEGF) during the training (A and B) and testing (C) for the three ages. ANOVA followed by post hoc Duncan’s test (mean ± standard error, * P < 0.05; ** P < 0.01; *** P < 0.001, n = 10 per group). In A, color lines and point markers connect the mean values for the groups in minute of observation during the training (WT-SAL in blue; AD-MSC-VEGF in green; AD-MSC in yellow; AD-SAL in red).

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