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. 2014 Mar 7;6:30. doi: 10.3389/fnagi.2014.00030

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Copyright © 2014 Garcia, Ornellas, Martin, Patti, Mello, Frussa-Filho, Han and Longo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunofluorescence and quantification of microglial cells in the hippocampus. Image of double-stained senile plaques (6E10 staining in green) and Iba-1⁺ cells (in red) in the hippocampus of AD-SAL animals at 12 months. Note the co-localization of Iba-1 and 6E10 in the merged image (scale bar 200 μm). The number of Iba-1⁺ cells counted in the WT, AD-SAL, AD-MSC and MSC-VEGF mice at 6, 9 and 12 months (two-way ANOVA followed by Tukey’s multiple comparisons test, mean ± standard error; * P < 0.05; ** P < 0.01; *** P < 0.001, n = 5 per group).

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