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. 2014 Mar 6;9(3):e89617. doi: 10.1371/journal.pone.0089617

Figure 1. Compound design and chemistry.

Figure 1

(a) Design of minimalist peptidomimetics with triazole scaffolds, and overlay of triazole-based mimic with type-I β-turn. (b) Strategy to build triazole-based β-turn mimics by click chemistry. (c) A general scheme to prepare bivalent mimics. (d) Structures of compounds, A that bind to TrkA.