Figure 8. Antagonists do not affect ligand-dependent neuritogenesis.
Cells expressing TrkC and p75 (nnr5-TrkC) were plated in full medium ± neurotrophin ± peptidomimetics (10 µM). Fields were photographed 72 h later. Neurite outgrowth was determined as percentage of cells with neurites (defined as length >2 cell bodies). Representative pictures from nnr5-TrkC for compound 1b are shown.