Table 1. Comparison between sequences of the bivalent mimics and neurotrophins.
compounds | 1a | 1b | 2c | 2d | 2e | 3f |
bind to | both TrkC and TrkA | only TrkC | ||||
R1R2-R3R4 | SK-IK | IR-IK | GT-EK | RI-TG | SM-GK | KS-KI |
Bold letters in sequences correspond to sequences in NGF, normal letters correspond to BDNF, and letters that are underlined correspond to NT-3.