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. 2014 Mar 4;82(9):798–805. doi: 10.1212/WNL.0000000000000169

Figure 3. Associations between magnetic resonance spectroscopy metabolites and clinical indices in mutation carriers.

Figure 3

(A) Negative linear relationship between gray matter N-acetyl-l-aspartate (NAA) and the Global Neuropsychological score, indicating lower NAA concentrations in those individuals with higher neuropsychological dysfunction. (B) Inverse relationship between lactate levels and the neurologic status, indicating higher lactate in those with pronounced neurologic impairment.