Table 2. Colonization of murine lungs with S. aureus and P. aeruginosa reference and clinical strains in competition experiments.
| PA14/Newman (n = 9a) | AA2/Newman (n = 9a) | AA43/Newman (n = 9a) | |
| Mortality, % (no. of dead/total mice) | 0 (0/9) | 0 (0/9) | 0 (0/9) |
| Co-infected b , % (no. of co-infected/surviving mice) | 89 (8/9) | 100 (9/9) | 78 (7/9) |
| P. aeruginosa infected c , % (no. of infected/surviving mice) | 100 (9/9) | 100 (9/9) | 78 (7/9) |
| S. aureus infected d , % (no. of infected/surviving mice) | 89 (8/9) | 100 (9/9) | 78 (7/9) |
| Total cfu/lung e | 3.3×104 | 6.7×103 | 5.8×103 |
| P. aeruginosa cfu/lung e | 2.9×104 | 4.5×103 | 2.7×103 |
| S. aureus cfu/lung e | 4.2×103 | 2.2×103 | 3.1×103 |
| CI f | 5.0 | 3.3 | 0.9 |
a
Pooled mice, analyzed in two independent experiments.
b
Co-infected mice, surviving after 18 hours from challenge.
c
Number of pooled mice infected with P. aeruginosa after 18 hours.
d
Number of pooled mice infected with S. aureus after 18 hours.
e
Median values are reported.
f
Competition Index.