Table 1.
Patient characteristics (n = 1176)
| Variable | Diabetes (n = 231) frequency, n (%) or median (inter-quartile range) | No diabetes (n = 945) frequency, n (%) or median (inter-quartile range) | P-value |
|---|---|---|---|
| Demographics | |||
| Age (years) | 61 (54–70) | 53 (40–64) | <0.001 |
| Female (%) | 81 (35) | 401 (42) | 0.041 |
| White race (%) | 197 (85) | 837 (89) | 0.17 |
| Black race (%) | 28 (12) | 74 (8) | 0.038 |
| General indication for CMR exam (%) | |||
| Known or suspected cardiomyopathy | 107 (46) | 386 (41) | 0.13 |
| Possible coronary disease/viability/vasodilator stress testing | 128 (55) | 331 (35) | <0.001 |
| Evaluation for arrhythmia substrate | 46 (20) | 287 (30) | 0.002 |
| Known or suspected mass or thrombus | 7 (3) | 47 (5) | 0.21 |
| Syncope evaluation | 7 (3) | 41 (4) | 0.37 |
| Comorbidity (%) | |||
| Hypertension | 197 (85) | 365 (39) | <0.001 |
| Dyslipidaemia | 153 (66) | 273 (29) | <0.001 |
| Current cigarette smoking | 42 (18) | 134 (14) | 0.13 |
| Atrial fibrillation or flutter | 20 (9) | 78 (8) | 0.84 |
| Hospitalized status | 101 (44) | 240 (25) | <0.001 |
| Coronary vessels with known stenosis>70% (>50% for left main) documented by angiography (%) | |||
| 0 | 161 (70) | 836 (88) | <0.001 for trend |
| 1 | 25 (11) | 49 (5) | |
| 2 | 11 (5) | 30 (3) | |
| 3 or left main involvement | 34 (15) | 30 (3) | |
| Prior coronary revascularization | 76 (33) | 129 (14) | <0.001 |
| Prior stroke | 17 (7) | 38 (4) | 0.031 |
| Acute myocardial infarction | 25 (11) | 42 (4) | <0.001 |
| Weight (kg) | 97 (82–115) | 83 (69–98) | <0.001 |
| Body mass index (kg/m2) | 31 (28–38) | 27. (24–32) | <0.001 |
| Medications (%) | |||
| ACEI, ARB, or aldosterone antagonists | 146 (63) | 335 (35) | <0.001 |
| Beta-blockers | 157 (68) | 402 (43) | <0.001 |
| Aspirin or other antiplatelet | 162 (70) | 384 (41) | <0.001 |
| Loop diuretics | 76 (33) | 165 (17) | <0.001 |
| Statin medication | 151 (65) | 282 (30) | <0.001 |
| Laboratory and CMR characteristics | |||
| Creatinine (mg/dL) | 1.0 (0.8–1.3) | 0.9 (0.8–1.1) | <0.001 |
| Glomerular filtration rate (mL/min/1.73 m2) | 75 (58–92) | 90 (74–94) | <0.001 |
| Haematocrit (%) | 37 (32–40) | 40 (36–43) | <0.001 |
| Ejection fraction (%) | 54 (39–63) | 58 (47–64) | <0.001 |
| Left ventricular mass index (g/m2) | 63 (54–76) | 56 (46–70) | <0.001 |
| End-diastolic volume index (mL/m2) | 80 (65–104) | 81 (68–97) | 0.91 |
| Non-ischaemic scar evident on LGE images (%) | 60 (26) | 203 (21) | 0.14 |
| Myocardial infarction evident on LGE images | 83 (36) | 153 (16) | <0.001 |
| Myocardial infarction size (% of left ventricular mass in those with MI; n = 71 for diabetes; n = 98 for no diabetes) (%) | 12% (5–23) | 13% (4–27) | 0.90 |