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. 2014 Mar 3;20:259–269.

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Copyright © 2014 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Adrenomedullin_22–52 inhibited HREC migration induced by high glucose. HRECs were analyzed for the ability to migrate into a wound area using a scratch wound assay. A: After HRECs were wounded using a 200 μl yellow micropipette tip, they were incubated with serum-free media containing high glucose with or without adrenomedullin_22–52 for 24 h. The re-endothelialized monolayer area was photographed. A magnification of × 200 was used to image the re-endothelialized monolayer area. B: The quantitative data of the migration distance were from three independent experiments. All values represent Mean±SD (n=3). * p<0.05 versus the 30 mM group. # p<0.05 versus the 5 mM group.