Figure 7.
Adrenomedullin22–52 inhibited the activation of PI3K by high glucose. After HRECs were treated with high glucose or high glucose plus different concentrations of adrenomedullin22–52 for 24 h, the protein level of PI3K was determined by western blot assay. A: Representative results from three independent runs of western blot. B: Ratios of PI3K to GAPDH were determined by western blot. The quantitative data of the ratios were collected from three independent experiments. All values represent Mean±SD (n=3). * p<0.05 versus the 30 mM group. # p<0.05 versus the 5 mM group.